Vortex Ring Formation in Diastolic Dysfunction: Phase Contrast MRI of Left Ventricular Filling
نویسندگان
چکیده
Introduction The formation of vortices during left ventricular (LV) filling (Fig. 1) has been noted in several investigations using phase contrast (PC) MRI [1,2], but the effect of diastolic dysfunction (DD) on vortex formation has not been investigated. We hypothesize that impaired relaxation (IR) and increased stiffness of the LV wall in DD, will substantially alter the kinetics of the vortices, which are highly sensitive to chamber properties. If true, quantitative measurements of vortex kinetics could fill the need for a continuous, non-invasive measure of diastolic function, which is currently lacking. In this pilot investigation a standardized method for visualizing and quantifying the LV vortex ring was developed and used to compare measures of LV diastolic vorticity in both normal and IR subjects.
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